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Patients reported the following extensive sexual dysfunction symptoms (mean precentage): 86.7% erectile dysfunction, 87.8% subjective arousal difficulties (sense of sexual excitement), 64.4% libido problems, 69.9% ejaculatory delay, 21.1% absent orgasm, and 5.5% other ejaculation and/or orgasm difficulties (ie, premature, retrograde, anejaculatory, lack of pleasure, pain).
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In the present study, piperine was found to promote DNA damage and cytotoxicity induced by benzo(a)pyrene (B(a)P) in cultured V-79 lung fibroblast cells.